27 thoughts on “Pandemic News Thread – July 17 – 23, 2022

  1. WHO declares monkeypox a public health emergency of international concern
    https://www.cnn.com/2022/07/23/health/monkeypox-who-intl/index.html
    Carma Hassan and Carolyn Sung, July 23, 2022

    [snip]

    I have decided that the global monkeypox outbreak represents a public health emergency of international concern,” WHO Director-General Tedros Adhanom Ghebreyesus announced on Saturday morning.

    Tedros said while the committee was unable to reach a consensus, he came to the decision after considering the five elements required on deciding whether an outbreak constitutes a public health emergency of international concern.

    He added that while he was declaring monkeypox a public health emergency of international concern, “For the moment this is an outbreak that’s concentrated among men who have sex with men, especially those who have multiple partners, that means that this is an outbreak that can be stopped with the right strategies in the right right groups.”

    [snip]

    Comment: Way too late. Also, there is no will anywhere to stop this pandemic, except in China. Same story as with coronavirus. Although no one has died outside of Africa, yet, this is coming.

    I think once millions are infected, people may respond differently to this one. A significant number of people are going to experience unbelievable levels of pain and permanent disfigurement. I think parents will take this one seriously when they see their small children writhing in pain on the floor and they are told that the hospitals are full. I think so. But people have been surprising me, always on the downside. We’ll see what choices they make once monkeypox starts spreading in daycares and schools.

  2. U.S. confirms first two cases of monkeypox in children — one case is in California
    https://www.cbsnews.com/news/monkeypox-children-first-cases-u-s-california/
    Alexander Tin July 22, 2022

    Health officials have confirmed the first two U.S. cases of monkeypox in children, the Centers for Disease Control and Prevention announced Friday.

    Both cases are “likely the result of household transmission” and “had no contact with each other,” the agency said in a statement.

    One is a toddler who lives in California and the other is in an infant who is not a resident of the U.S. and was “transiting through” the Washington, D.C. area when the test was done.

    [snip]

    Children, especially those under 8 years old, are among those the Centers for Disease Control and Prevention warns are at “especially increased risk” for severe monkeypox disease.

    Last week, CDC officials told reporters that at that point, they were only aware of monkeypox cases in adults. But the agency acknowledged that state and local health authorities had only relayed additional demographic information to them for less than half of all tallied cases.

    The agency is also now aware of at least eight cases in people who identify as cisgender women, McQuiston said.

    [snip]

    As of Friday, the CDC had tallied a total of 2,891 cases of monkeypox in the U.S. across 44 states, as well as the District of Columbia and Puerto Rico.

    While the virus has led to many adult patients enduring pain and sometimes severe complications, many of the cases have so far resolved after several weeks without intensive treatment or hospitalization.

    But health authorities warn that monkeypox may pose greater dangers to young children.

    In countries that have seen an endemic spread of monkeypox before 2022, the World Health Organization warns that young children have died at higher rates from the disease.

    During the current outbreak, a handful of countries have also spotted cases of monkeypox in children under 18 years old.

    The CDC’s European counterpart tallied at least five cases on Wednesday. Authorities in Spain’s capital announced on Wednesday that they had detected a case in a 7-month-old baby who likely caught the virus from their parents.

    In the Netherlands, doctors reported they were unable to identify how a boy under 10 years old had caught the virus. No secondary cases were identified from the infection.

    As is the case with adults, medicines like the antiviral tecovirimat or TPOXX are available for treating monkeypox cases in children and have been safely given to children in the past. However, the CDC says no clinical studies have specifically investigated use of the antiviral in children.

    Comment: Adult men are in the hospital because the pain is so bad they can’t handle it with prescription medicine at home. Imagine inflicting this kind of pain on small children. Adult are also in the hospital because they can’t swallow. Small children can die of dehydration very quickly if they don’t drink enough water. Given current guidelines and practices, we can expect millions of American children to be infected with monkeypox within the next year unless something, someone, changes. Some of them are almost certain to die.

  3. First cases of monkeypox in children in U.S. confirmed
    https://www.washingtonpost.com/health/2022/07/22/first-monkeypox-cases-children-united-states/
    Lena H. Sun, Fenit Nirappil July 22, 2022

    The first two U.S. cases of monkeypox in children have been confirmed as part of a record outbreak of more than 2,500 infections nationwide, a top health official said Friday.

    The pediatric cases, detected this week in an infant and a toddler, are likely the result of household transmission, according to the Centers for Disease Control and Prevention. CDC Director Rochelle Walensky disclosed the development in a Washington Post Live interview Friday.

    CDC and public health authorities are still investigating how the children became infected. The two cases are unrelated and in different jurisdictions, the agency said in a statement. The toddler is in California; the infant’s case was confirmed while the family was traveling in Washington, D.C., but they are not residents of this country.

    Walensky, in her interview, said the cases link back to individuals who come from the men who have sex with men community. But the investigations are ongoing to “know or understand” the connection to that community, another CDC official said.

    “While both children have monkeypox symptoms, they are in good health,” and receiving an antiviral treatment for the disease, the CDC said.

    [snip]

    During the current outbreak, a few countries have confirmed a handful of monkeypox cases in those under 18. The CDC’s European counterpart tallied at least five cases on Wednesday. Authorities in Spain announced Wednesday they had detected a case in a 7-month-old.

    [snip]

    The antiviral medication TPoxx is also available to treat people with severe cases, although patients and doctors complain it has been difficult to access because of an onerous process required by the federal government. The CDC announced Friday it was eliminating some requirements to ease access.

    Comment: There will be hundreds of thousands of monkeypox cases in the US soon. Do we have enough TPoxx for all of them? What about when millions of children are infected?

  4. ‘Nobody’s acting like this is an emergency’: Act Up veteran Peter Staley condemns US monkeypox response
    https://www.theguardian.com/politics/2022/jul/22/peter-staley-monkeypox-response-us-interview
    Wilfred Chan 22 Jul 2022

    Peter Staley makes an unlikely member of the US public health establishment. In the late 1980s and 1990s, the Aids activist was arrested 10 times for dramatic protests against government agencies and healthcare companies that included blocking traffic, breaking into buildings, and chaining himself to the balcony of the New York Stock Exchange.

    But Staley’s years of criticizing the nation’s decision makers on health crises, particularly as part of the legendary Aids pressure group Act Up New York, have brought him into the fold. As the co-founder of the group PrEP4All, Staley has the director of the Centers for Disease Control, Rochelle Walensky, “on speed dial”. He regularly emails with the National Security Council’s pandemic chief, Raj Panjabi. And he has become close friends with Dr Anthony Fauci, who he says frequently turned to him for advice during the coronavirus pandemic.

    Those friendships are now being tested as Staley sounds the alarm on the federal government’s response to monkeypox, which he calls a “fucking mess”.

    “We’re close to the point where we’re wanting to call for the resignations of people we consider friends,” he told me by phone on Wednesday. “Unlike what a lot of people are saying, it’s not Aids 2.0, where we have a government filled with homophobes who don’t care about us. But it is Covid 2.0. It’s basically a copy and paste.”

    [snip]

    Staley says he’s still looking for clear answers, and that he has noticed his communication is “beginning to degrade with people at the top” as he’s stepped up his criticism. But if he has one regret, it’s that he and other activists didn’t blast them sooner.

    “We dropped the ball,” he tells me. “We just should have stayed in screaming mode every step of the way.”

    Comment: Yep.

  5. Risk of Reinfection, Vaccine Protection, and Severity of Infection with the BA.5 Omicron Subvariant: A Danish Nation-Wide Population-Based Study
    https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4165630
    Hansen and Friis 18 July 2022

    [snip]

    We found a high protection against BA.5 from prior omicron infection in triple-vaccinated individuals, and similar vaccine effectiveness for BA.5 infection as currently for BA.2. In an analysis adjusted for covariates, BA.5 infection was associated with an increased risk of hospitalisation which needs confirmation and continued surveillance as hospitalisations were low and stable during the study period.

    [snip]

  6. House Oversight chair calls on HHS to address ‘barriers’ to monkeypox treatments
    https://thehill.com/policy/healthcare/3569223-house-oversight-chair-calls-on-hhs-to-address-barriers-to-monkeypox-treatments/
    Joseph Choi

    Rep. Carolyn Maloney (D-N.Y.), chair of the House Oversight and Reform Committee, on Wednesday asked the Department of Health and Human Services (HHS) to address the “barriers” to monkeypox treatment that people have reported dealing with so far.

    Maloney said she was concerned by the sparse availability of vaccines for monkeypox as well as the limited capacity for testing for the virus that has been noted in the U.S. She noted how quickly appointments to receive vaccines like Jynneos filled up in major cities as well as the lack of rapid testing for monkeypox.

    “In addition to access to vaccines and testing, patients who have contracted MPV must be able to obtain appropriate treatment,” Maloney wrote.

    “In recent days, reports have emerged that patients are facing barriers and extreme difficulties in accessing TPOXX, the only antiviral medication clinically shown to decrease duration of disease and reduce the risk of fatality,” the congresswoman added, noting that the Centers for Disease Control and Prevention (CDC) currently approves the administration of the drug on a case-by-case basis.

    “These barriers to accessing treatment implicate health equity, as evidence suggests that the patients most likely to access TPOXX currently have private insurance or a primary care physician, which many Americans lack,” she added.

  7. Senate Health chair says she’s ‘concerned’ about U.S. monkeypox response
    https://thehill.com/homenews/senate/3567373-senate-health-chair-says-shes-concerned-with-u-s-monkeypox-response
    Joseph Choi – 07/20/22

    Sen. Patty Murray (D-Wash.), chairwoman of the Senate Committee on Health, Education, Labor and Pensions, said she is “concerned” by the state of the U.S. monkeypox response in a letter to Health and Human Services (HHS) Secretary Xavier Becerra.

    “As I have raised on multiple calls with the Administration, I am concerned with the state of the U.S. response to monkeypox,” Murray said in her letter Tuesday. “The spread of monkeypox is a reminder that our work to protect families and strengthen our preparedness and response system is far from complete and cannot end with the COVID-19 pandemic.”

    [snip]

    Comment: The COVID-19 pandemic isn’t over and isn’t likely to be over any time soon. It is entirely possible that we will get a strain that completely escapes vaccination and is more lethal than the original strain.

    Many knowledgeable people realize that the CDC’s response to monkeypox is bad, and have said so. What they haven’t said, out loud, yet, is that the response is starting to look fishy. Even if you assume that Walensky is a complete moron, it is hard to explain what she is doing. What it looks like is a deliberate campaign to allow monkeypox to spread as widely as possible. The CDC is doing just enough, just slowly enough to look like it is doing something but not enough to stop the spread. Walensky has access to numbers. These numbers make it clear exactly how much vaccine should have have been deployed and where and when to stop the virus. She is controlling the flow of vaccine in a way that allows the virus to spread. That is different from what a person over their head would do.

    President Biden could fire Walensky any time he wants and replace her with someone competent. Yet, despite the fact that her actions are harming one of his key constituencies, he allows her to continue in her post.

    Why is he doing this? I am running out of benign explanations.

  8. Survey finds nurses are leaving over coronavirus stress
    https://www.washingtonpost.com/business/economy/2022/07/20/e16d47bc-083d-11ed-9a88-9b2bc12f7753_story.html
    July 20, 2022

    A survey of 2,500 nurses released Wednesday found that 64 percent are looking to leave the health-care profession, a nearly 40 percent increase from a similar survey a year ago. Three-quarters of those surveyed said they have experienced burnout since the coronavirus pandemic began, and half said they had suffered feelings of trauma, extreme stress or post-traumatic stress disorder.

    [snip]

  9. EU [European Union] Population Declines for Its Second Year
    https://www.statista.com/chart/27779/eu-population-net-figures/
    Anna Fleck, Jul 15, 2022

    The EU’s population has decreased for the second year running, reflecting the devastating impacts of the coronavirus, according to Eurostat. The bloc’s population had been increasing year on year, hitting a pre-pandemic peak of 447,485,231 people on January 1, 2020. Where there were 447,000,548 people registered across the 27-country bloc in 2021, the number dropped to 446,828,803 by the start of this year.

  10. How the ‘Centaurus’ Omicron subvariant could become dominant worldwide
    https://www.euronews.com/next/2022/07/15/is-covid-ever-ending-meet-centaurus-the-latest-omicron-subvariant-that-could-become-domina
    Luke Hurst • Updated: 18/07/2022

    [snip]

    BA.2.75 is already becoming dominant in India, after it was first detected there in May.The subvariant has now been found in dozens of countries including the UK, Germany, and the Netherlands.

    [snip]

    “What we’re seeing with this new BA.2.75 is that it is spreading in countries where there have been high levels of vaccination, so it does seem that this virus is able to get around some of the pre-existing immunity,” said Gaunt.

    [snip]

    Comment: This article has quotes from public health officials indicating that we should just accept that Covid will keep infecting us. Not one mention of Long Covid in the entire article.

  11. Researchers assess the evolution and diversity of monkeypox virus genomes using phylogenomic analysis
    https://www.news-medical.net/news/20220718/Researchers-assess-the-evolution-and-diversity-of-monkeypox-virus-genomes-using-phylogenomic-analysis.aspx
    Bhavana Kunkalikar Jul 18 2022

    [snip]

    The study findings showed that all the genomes detected in the current MPXV outbreak among humans in 2022 have a remarkable monophyletic lineage compared to the lineages observed in the past human MPXV outbreaks. This striking divergence from the past lineages highlights the increased mutational signature, indicating an accelerated evolutionary path. The study suggested that the noted genomic variations could be responsible for the efficient transmission and the increased number of MPXV infections observed in the 2022 MPXV outbreak.

    Journal reference:

    Luna, N. et al. (2022) “Phylogenomic analysis of the monkeypox virus (MPXV) 2022 outbreak: Emergence of a novel viral lineage?”, Travel Medicine and Infectious Disease, p. 102402. doi: 10.1016/j.tmaid.2022.102402. https://www.sciencedirect.com/science/article/abs/pii/S147789392200148X

  12. Health officials confirm case of monkeypox in UT Austin community
    https://www.kvue.com/article/news/local/monkeypox-case-ut-austin-community/269-9d8fce4f-ee84-464d-b1c6-6fdf6bde2c1c
    July 18, 2022

    A case of monkeypox has been confirmed within the University of Texas at Austin community, according to a spokesperson for University Health Services.

    [snip]

    In a Thursday press conference regarding monkeypox in the area, Austin Public Health officials said there were nine confirmed cases of the virus and eight presumptive cases. Officials said that the virus is now considered “community spread” as new infections have begun to appear in people without a history of travel.

    [snip]

  13. Monkeypox treatments are difficult to get despite the nation’s large stockpile
    https://www.wkar.org/2022-07-18/monkeypox-treatments-are-difficult-to-get-despite-the-nations-large-stockpile
    Pien Huang July 18, 2022

    There are more than 1,900 confirmed cases of monkeypox in the U.S. The virus causes painful sores that can last for weeks. There are anti-viral pills that can help people recover faster, but patients and their advocates say the treatments are too hard to get. NPR’s Pien Huang explains why.

    PIEN HUANG, BYLINE: The treatment is called TPOXX, and it’s a two-week course of pills.

    [snip]

    The federal government controls the supply, but officials with the CDC and the Department of Health and Human Services declined to tell NPR how much they’ve given out. TPOXX is made by SIGA, a drugmaker that’s worked closely with the U.S. government for years. Phil Gomez is the company’s CEO.

    [snip]

    HUANG: But even though the drug worked against monkeypox in monkeys, the FDA only approved its use for smallpox in humans. And that has created dense ribbons of red tape for doctors and patients in the current monkeypox outbreak. There’s enough TPOXX in the strategic national stockpile for 1.7 million people. Dr. Robert Pitts, an infectious disease specialist at NYU Langone Health, has prescribed it to seven. Each time it takes three to four hours of paperwork.

    ROBERT PITTS: Like, every time I send a TPOXX prescription, I’m very cognizant of, like, this is what the patient needs. But the work that I’m going to put into this is, like, more time that I have.

    [snip]

    Comment: If Walensky is simply stupid, why does she order her officials to hide the number of TPOXX doses administered? Isn’t that evidence of malicious intent?

  14. Doctors treating monkeypox complain of ‘daunting’ paperwork, obstacles
    https://www.washingtonpost.com/health/2022/07/15/monkeypox-response-vaccine-treatment-obstacles-adams/
    Dan Diamond July 15, 2022

    Roy Gulick wants to give his monkeypox patients the best possible care. But he and his doctors simply don’t have enough hours in the day to complete dozens of pages of paperwork every time they need to pry medicine out of the Strategic National Stockpile.

    [snip]

    Physicians’ struggles to prescribe Tpoxx, an antiviral approved to treat smallpox, which is from the same family of viruses as monkeypox, are among a slew of obstacles related to testing, treatment and vaccination that experts say is contributing to a plodding national response that they fear is not keeping up with the virus’s spread. Some worry that the window is closing to prevent the virus from becoming permanently entrenched in this country, with more than 1,400 confirmed infections across 42 states — and hundreds or thousands of additional infections suspected, predominantly in the gay and bisexual community.

    “The story that the White House has told us is … frankly insulting to a community that is right now facing an out-of-control outbreak without being able to access the tools they need to protect their health,” said James Krellenstein, co-founder of PrEP4All, a public health advocacy group that has pressed the Biden administration on Tpoxx and other issues.

    [snip]

    As with coronavirus, doctors, patients, public health experts and even some administration officials are frustrated with decisions by the Centers for Disease Control and Prevention and Food and Drug Administration, saying they have taken too conservative an approach to the rapidly widening outbreak and should have further expedited tests, vaccines and treatments. Many warn that if the United States can’t respond quickly and effectively to an established infectious disease with known treatments and vaccines, it is likely unprepared to combat a new pathogen, or another threat on the scale of coronavirus.

    [snip]

    “Monkeypox was a slowly expanding crisis; we had plenty of time to prepare. The fact that CDC struggled with so many parts of response should prompt Congress to make fundamental changes to scope and nexus of pandemic planning as matter of national security. “https://t.co/mUjZ2HeaOm
    — Scott Gottlieb, MD (@ScottGottliebMD) July 15, 2022

    [snip]

    Comment: Indeed.

    President Biden could fire the head of the CDC and the FDA any time he wants and replace them with people who would actually try to save people’s lives. But he doesn’t. What does this say about him?

    Certain “science” journalists have become apologists for the CDC and the Biden administration’s handling of monkeypox. What does this say about them?

  15. Federal probe sought over NYC monkeypox vaccine rollout
    https://pix11.com/news/local-news/federal-probe-sought-over-nyc-monkeypox-vaccine-rollout/
    James Ford July 18, 2022

    The handling of the monkeypox outbreak in New York by federal and local health officials was the target of criticism on Monday.

    A variety of people, from a local member of Congress, to community leaders and people trying to get the monkeypox vaccine, said that protecting the public from the virus should be much easier than it’s been.

    As part of the criticism, Rep. Ritchie Torres, an openly gay Democrat whose district is in the Bronx, called for a federal investigation of the Health and Human Services Department’s handling of the monkeypox epidemic.

    “The United States has a long and ugly history of callously ignoring the public health needs of the LGBTQ community,” Torres said at a news conference on Monday morning, “and history seems to be repeating itself.”

    [snip]

    He specifically cited a delay in inspection of more than a million doses of monkeypox vaccine earmarked for use in the U.S. that went uninspected by the FDA at a facility in Denmark.

    The doses “were left to languish in freezers,” Torres said, and by the time the FDA was able to reach the facility and inspect, the doses were expired.

    [snip]

    Comment: People should not assume that those who say they are your friends, really are your friends. “By their deeds you shall know them.”

  16. Former FDA chief warns U.S. has “failed to contain” monkeypox
    https://www.axios.com/2022/07/17/monkeypox-scott-gottlieb-contain
    Ivana Saric July 17, 2022

    “I think the window for getting control of this and containing it probably has closed, and if it hasn’t closed it’s certainly starting to close,” Gottlieb said.

    “We’re probably detecting just a fraction of the actual cases because we had for a very long time a very narrow case definition on who got tested,” he added.

    “By and large, we’re looking in the community of men who have sex with men and STD clinics. So we’re looking there. We’re finding cases there. But it’s a fact that there’s cases outside that community right now. We’re not picking them up because we’re not looking there.”

    “I wouldn’t be surprised if there’s thousands of cases right now,” he added of the U.S. case count.

    “We made a lot of the same mistakes we made with COVID with this. Having a narrow case definition, not enough testing early enough, not providing a vaccine in an aggressive fashion. … While it’s not going to explode because it’s harder for the virus to spread, it will be persistent.”

    [snip]

    Comment: Monkeypox is like a tidal wave. It will just get bigger and bigger. There won’t be separate waves. The only way to stop it without shutting down the entire country is with a massive seawall of vaccinations. This won’t happen. The limited testing and limited vaccine availability will ensure that the virus will keep spreading. By the time sufficient vaccines are available for every American, 300 million doses, it is entirely possible that monkeypox will have mutated to something worse than it is now.

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